At noon on March 26, 2025, Professor Cai Kang from the College of Chemistry, Nankai University, visited our group and delivered a presentation titled “High-Affinity Aqueous Molecular Recognition and Function”. He introduced the features and applications of the newly developed C[4]BINOL macrocycle by his research team. Additionally, he discussed the potential of machine learning in enhancing aqueous molecular recognition. During the session, Professor Cai engaged in diverse discussions with the students, and everyone found the experience highly informative and beneficial.